Arch, I'm not surprised that Axiom wouldn't really be able to answer your question as every room and scenario will be different.
When I was a kid, I build a turntable base to isolate the TT from infrasonics/bass. It was basically a "topless" box filled with sand, with a plywood, undersized "top" that the turntable sat on. This de-coupled the TT from sitting on anything other than that one piece of plywood, which touched nothing but sand. It worked well, and the same general design could be reworked for a speaker.
Still, though, bass waves are going to travel through floors if the speakers are playing loudly, though decoupling them might help.
Buy sand from Home Depot so you don't import Platypus eggs from the beach and wake to a room full of baby platypuss' (plattypussi?).
I don't have a photo so made this up to help describe what I'm talking about:
