How about moving the TV to the bottom left corner (where the sub is) and adjust accordingly? Maybe have the couch on the right wall (still five feet out or so - looking out the new window onto the roses) and place some of the other chairs around the top left of the room. Then, your couch will be perpendicular (sp?) to both the fireplace (focal point), TV (focal point) and looking right at the expensive windoe (focal point).
Again, you've got lots of options. Take a saturday, get some sweat pants on, invite a buddy over (entice him with beer, if necc.) and start moving stuff around and sitting to see how it feels. Get your wife involved - you never know what kind of input she may have that is more compromising than you first thought.
