Hi Bryan,
I am an m22ti owner. And I recently ordered the m50ti's, which I returned. The midrange of the m22s make quite a difference. The m50s were really laid back sounding and didn't possess the soundstage of the m22s. I've read that the m40s are even more laid back. The clarity and the soundstage of the m22s are simply astounding. If you like a forward sounding speaker with incredible soundstage and clarity the m22s are the one. But, if you like a laid back sound the m40s will probably do the trick. My m50s were more pleasant sounding, but they were dull sounding to me. To me the m22s with a sub are hard to beat. Check out the stands at ac4l.com.
