Guess it depends on the music / movies split. For a pure music system it's a no-brainer. As Ford Prefect says, M60s on their own cover the bass just fine for music.

If you're going to be listening to movies a fair amount I would have to vote for M22 + sub -- my sub is out on loan right now so I'm watching movies on M60s without sub, and it's really not the same.

Sorry this is not like "what receiver should I get" where we all agree on the answer

M60ti, VP180, QS8, M2ti, EP500, PC-Plus 20-39
M5HP, M40ti, Sierra-1
LFR1100 active, ADA1500-4 and -8