For that kind of layout I would go with 60s and spend any extra $$ on sub not mains. VERY roughly you need to size your mains based on distance from speakers to listening position but size the sub based on the size of the entire room. It's not really that simple but it's a good start...

M60ti, VP180, QS8, M2ti, EP500, PC-Plus 20-39
M5HP, M40ti, Sierra-1
LFR1100 active, ADA1500-4 and -8