I'm sure you meant crossover knob on the sub, not the volume? The receiver handles the management for speakers set to small, so get the sub crossover knob out of the way.

For most speakers 80hz is a good starting point. That should work great for the 22's. On my Denon I have the Q's set to 90hz and the VP150 set to 80hz as well..

M80s VP180 4xM22ow 4xM3ic EP600 2xEP350
AnthemAVM60 Outlaw7700 EmoA500 Epson5040UB FluanceRT85