AMD has been hit occasionally with some compatibility issues. I'm not so sure they haven't been caused more by third-party chipsets (SiS in particular) than problems with the procs or their microcode. The result has been that many people have sworn off AMD chips forever, price/performance ratios be damned. I have a mix of Intel and AMD at home. As an aside, I personally am a big fan of Asus motherboards and have gotten burned by MSI MB's in the past (not literally, althought I have had procs go up in smoke before).
