As for the AS sereies installation, they will work on the standard 2 x 4 wall that is 16" OC. If using an exterior wall, the insulation will need to be cut out some, so the speaker will snap into the frame once installed. Axiom provides a template for making the cut out area for the AS frame, so knowing exactly where the wall studs are located helps. The W100 & W150 are less than 14" in width, and the distance between 16" OC studs should be 14.5" in a perfect world, and are usually close to that dimension.
The AS sereis does not need any special framing of the wall, the in wall bracket is desigined very well and uses a series of screws to compress the two metal frames to the drywall. Took me about 10 minutes per speaker to install them, a bit longer to install some cut in boxes in the wall and pull wires from them to the speaker opening.