I figured I'd chime in with my findings this weekend. I originally set my all my speakers to small on my Pioneer VSX74. I'm running M60s in the front, VP150 center, QS4 rears, and a SVS 25-31PCI sub. I calibrated with SPL and had the SVS running about 3db hot over the other speakers.
For some reason the sound just didn't seem to "right" to me. With 5.1 it was good, but any broadcast pro logic sounds, or 2 channel stereo was missing something. I recalibrated with the M60s as large and I feel it gave me a better overall sound across all listening options.
