Hi canesfan,
The Axiom M22s are virtually indistinguishable from the Paradigm Ref. Studio 20s (I own both), except for a little more midrange detail from the 22s and without the slight bass hump of the Studio 20s.
Moving up the line, Axiom's M60s and M80s are comparable--actually a bit more neutral--than Paradigm's Studio 100s, again without the little Paradigm bass hump present in all their speakers. The latter hump initially gives the impression of more bass at the expense of midrange detail and transparency. Essentially there are minor differences in bass, midrange, and treble balance.
Regards,
