Yes, I would try turning it around. It will allow the drivers to breathe a bit, and acts just like a home sub in the corner with a "loading" effect. If you don't like the change, just spin it back around.
There are a couple of other things you may want to try that have worked for me in the past.
In the Cutlass, I removed the sound deadening material beween the seat & trunk. In the one Accord, I cut an opening in the centre of the rear deck and just put a dummy speaker grill there. In the second Accord, I did the same thing, but covered the entire rear deck with grill material. (I was geting older, and it was too nice of a car to see an actual speaker grill)
