2x6, although you don't have the numbers yet, the inference is that this's a pretty big room. Although the LCDs are gaining ground quickly(e.g., the Sony 52XBR4), for a big screen I'd suggest considering a top plasma, such as the Panasonic TH-58PZ750U.
For the mains, sure M80s. For the center, don't know why the Ws would be especially appropriate, but my thought would lean toward a third M80 or an M60.
Four QS8s for the surrounds and put a pair of EP600s at the midpoints of the front and back walls or the side walls.
This concept of a "blank check" is making me dizzy spending all this money, so I'll stop now.
