Yes, running combined twisted pair does make a difference... you get rid of induction... in twisted pair. Doubled up loose wire you won't see that benefit:

http://www.hometheaterhifi.com/volume_10_2/ultralink-CL414-cable-5-2003.html

I can't take credit for that link. I got it from another thread on this board a long time ago.

According to the article above, using doubled 14g results in the current capacity/resistance of an 11g wire. I figured I didn't quite need that so I looked up the stats on 16g.

Twisted pair 14g:
- Conductor diameter close to 8g? Don't recall
- Resistance close to 11g
- no induction

Twisted pair 16g:
- Conductor diameter close to 10g
- Resistance of 13g
- no induction

Personally I'm getting my stuff at the end of this month and intend to go with 16g 4 conducter in wall, from monoprice.

Hope this helps:
snazzed