There has been one posting about a set LCR VP150's set up across the front in a large open space, where are those pics?. I would think 3 VP100s across the front would work just as well and has been mentioned ensure the sub is near the front and set the crossover around 100hz.
But if you have enough room to run, say 2 M2's and a VP100 for a center I would go this route as the M2's will have better horizontal dispersion as Dean(grunt) mentioned. this wil help ensure all seating positions have better sound.
