Not sure why or how it would set the EP350 x-over. Are you referring to where it sets LFE?
Audyssey reconfigures x-over points to accommodate room reflections and oddities that can affect equal SQ throughout the room. It does this be applying a slew of filters throughout the speaker’s frequency response. Some people like it, some don’t.
You can raise crossover levels without adversely affected the filters that Audyssey applies, but don’t ever lower them. You can also change channel levels wherever you want without affecting the Audyssey filters, and it is strongly recommended that you verify channel levels with a meter. I would set everything within .5 DB, and then raise the center channel 2 DB or higher to your liking. Set your sub 5 DB higher than the mains.
I would set the LFE crossover to 120. Set the QS-8 to 80 and set the M60’s to 80. Try this and see how it sounds to you. You could also try setting the M60’s at 60 and see which you prefer.
