Since you're 12' away, you should probably go with the VP150. You'll also get a little wider dispersion (if you need it).

How far apart are your current surround speakers? If they are 12 - 15' apart (or more) then you should also consider the QS8's if your budget allows. Plus if you've got a big loft with a lot of air around you, then the QS8's will fill the room better.

Jason

M80 HP v4, VP160 v4, QS8 v1 (3 in 6.1 layout), SVS PB12-Plus/2, Parasound Halo A21, Denon AVR-X4100W