I'll agree with John's answer on midbass. I will add that more often than not, issues with a given frequency range are a room problem more than a speaker problem.
The differences between the M22 M60 and M80 midbass are for the most part subtle and all three are excellent performers.
The M22s, as a bookshelf will roll off higher at the bottom end (70Hz -3db), so you will lose some midbass and bass unless you pair them with a sub.
so is midbase important if you're pairing your speakers up with a great subwoofer and crossing over at 80Hz?