I've calibrated my system and listen to it both with Audyssey on and off, sounds far better with Audyssey on. Most people that don't like Audyssey, don't run the setup correctly or assume it is like previous setup products from the past. My VP180 is a huge improvement over my 150, can't comment on the 160. One thing you could try is to bump up the dB levels of the center channel a little.

M80s VP180 4xM22ow 4xM3ic EP600 2xEP350
AnthemAVM60 Outlaw7700 EmoA500 Epson5040UB FluanceRT85