I think you would be surprised at how well the M22's integrate with a good subwoofer. That said, for the money you would spend on M22's, stands, & a sub you should probably go with the M50's, as long as the bass extension of a sub is not critical to you.

Also, have you checked out the factory outlet? The pair I received didn't seem to have any real visible defect.

Good luck with the decision!