That is over 3800cu ft of space...
Maybe it was just Alan from Axiom "upselling" me, but I have about that much volume in my area, but with a ceiling of 8 feet, it is more spread out. I was going to go with the same setup you are, but he said that I would be better off moving up to the M60ti fronts, and making sure I had a nice big (12"+ sub)... This was with me sitting about 11 feet away from the speakers too.
With that said, I am sure that there ARE benefits of going to the M60ti for more than frequency range, but for room volume compensation, but I wonder how much it really matters with speakers that are pointed right at the listening position. I am sure that I have some measurable gain in sound with the M60ti for air volume, but I wonder if it is worth 2x the price... Hmmmm.
Now that I have rambled on, you will be very happy with your M22 fronts, but if you have the money to spend (wish I had more) you may want to look at the M60ti, if not, grab a set of M22 speakers and be happy, be very happy...
