Bruce, the first thing that pops into my mind, while reading your post, is "If you liked your M22s, you will DEFINITELY "be satisfied" the M60s." I initially had M22s, which I liked very much, but felt I wanted "more." I switched to the M60s and was very pleased with the change.
Since I've never heard Polk or PSB speakers, I can't speak to the Polk vs. PSB vs. Axiom thing. Giving you the best advice I can, I'd say get as much information as possible about all 3 brands, try to sift out the "my speakers are better than everybody else's" BS, listen to the little man inside, and make the best decision of which you are capable. Then sit back, listen to the music, and be happy.
(Sorry! I know that philosophical rant isn't much help, but speaker preference is totally subjective.
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