Mike, I always like to visit Fisherman's Wharf and Ghirardelli Square when I'm down there, I've haven't been to Alcatraz yet but I hear it's cool.
The only restaurant that really stood out for me was Acquerello, it's a pricy Italian place but great.
But when you go to Napa, if you want to eat at one of the best restaurants in the world, go to French Laundry in Yountville, reservations must be made 2 months in advance.

A computer once beat me at chess, but it was no match for me at kick boxing.