Rodney, welcome. My view would be that the M22s, supported by a good sub, would certainly be enough for that size room, but since you really want the M60s, no problem would exist with them. It looks like you'd be sitting about 8' away from them, which should be far enough for the drivers to "blend". You'd be too far from the back wall to put the surrounds(which are side surrounds)there. About 6' up at the front edge of the window farther back, with the other directly opposite on the open wall, should be fine.
