I like the uummpphh (sp?). And I definitely like my music to come from the mains rather than the sub so large setting is more convenient.
Small settings, with the sub at 12 o'clock, provided louder sound but it did seem less integrated.
I keep switching back and forth. For Monsoon Wedding, a very nice Indian movie with surprisingly good sound effects, I had to switch the mains to small to understand the dialogue. Same with Gosford Park.