I have the 676, which is pretty much the same as the 659, barring button moves. I prefer the 676's button position to just about any of the other remotes, including the 880. The 880s buttons are far too similar, especially if you're doing it by feel.
The 676 does just about everything I want it to, with a minimum of fuss. Like I was complaining about, I want discreet codes for disc selection and ff/rev on my DVD changer, but that's not really Harmony's fault.

I am the Doctor, and THIS... is my SPOON!