I have noticed that some of the pro amps have higher noise ratios than the home audio amps, which may lead to noisy/staticy sounds through your speakers during quiet times. This would not be a concern in a DJ situation.

From all my looking, Qsc appears to be the near the top of the pile as far as home audio specs in DJ amp and cost/watt.

Jason
M80 v2
VP160 v3
QS8 v2
PB13 Ultra
Denon 3808
Samsung 85" Q70