For me in my room the best setup is 3 M80s across the front which gives me a perfect front soundstage for both movies and music including multi-channel. QS8 surrounds and rears but could probably get by with M2 rears. QS4 height speakers and M2 wide speakers.
Although it’s recommended to use identical speakers all the way around I’ve found that for almost everything movies, music including the multi-channel stuff the QS8s beat direct radiating speakers as surrounds and often rears depending on the distance.
But as was said it depends on your room and any other constraints.
