I have mentioned this before, however, I have had the opportunity to try both in an HT application and for me, there was a noticeable difference between the M22s, used in an L/R and sub combo and the use of M60s(now M80s) and sub in the same configuration. It came in the form of power handling in that the M22s seemed to strain a little bit in the mid/low bass region at high volumes whereas the M60s/M80s handled sound in the same region without a hitch.

With music, it was less noticeable although realistically nothing can replace those extra drivers and substantially bigger cabinets of the floor-standers.