I believe that you are going to drive yourself crazy by second guessing all the time.

The difference in sound in the real world will be absolutely negligible, especially if you are using a decent sub or two. My VP160 is teamed up with M22s that don't have the 6.5" drivers that the VP160 does; however, they complement each other flawlessly.

While nice to have identical drivers in all of the speakers across the front, in the real world, timber matching is way over hyped IMO...