That is an interesting question, one that I was thinking about for my setup. I have M80/QS8/VP150/2xEP350's with a projector in a similar sized room. One of my thoughts was how much real estate the M80's take up beside the screen.

The sound is great...but the "less noticeable" M5's with dual subs might be a more natural fit. I know Tom (TAM - exlabdriver) has bookshelves and subs and loves the sound.

Of course my next upgrade will be the 150 to a 180 at some-point.

P.S., I still remember the look on Tom's face when he was describing the set up and sound to me at the Axiom 35th Anniversary party! :-)