Unless your room is HUGE I can't imagine three M60ti's up front wouldn't be enough. That's a LOT of speaker.

*sigh* I wish I had a dedicated room for HT.

If I did there's no doubt I'd go the FP route with three M60ti's up front. Two pair of QS8's for surrounds and rears, and likely dual EP500's. (If I'm not mistaken two subs are easier to setup and get flat responses from than one, and two EP500's are likely more sub than I'd ever really need!)

...someday.