I vote for the M22/350 combo first and then if you do not like the sound or feel it to be lacking, you can always upgrade to the M60s. I have the M22s and just recently hooked them up in the main HT with my big PB13 Ultra and it sounds very good in there right now; not as good as the M80's/PB13 but very good.

Jason
M80 v2
VP160 v3
QS8 v2
PB13 Ultra
Denon 3808
Samsung 85" Q70