I've had my M22s (with two subs) in about the same size apartment/living room as yours for about three years now, and I've been extremely pleased. My only complaint (and it's one that's common for the other apartment dwellers on this board) has been that I do have to be a conciencious tennant and a decent neighbor.
With those kind of restrictions in mind, the 22s are a fantastic choice. They're more than capable of filling the room (and equally capable of annoying your neighbors), and they're wonderfully accurate speakers. In short, they're perfect for the home you're currently living in. The only question you should be asking yourself is whether you want to stretch for a pair of floorstanders so you'll be just as happy later on when you finally move out of your apartment.
