I feel the visual issue goes away with time, much like I am already use to the 58" plasma, which i know will seem too small in my new house.

I would try the speakers in the spots you are suggesting and go with the ones that sound the best. You can use ladders, friends, etc. as temp stands to get an idea of which spot works \:\)

M80 v2
VP160 v3
QS8 v2
PB13 Ultra
Denon 3808
Samsung 85" Q70