Audyssey works out well for me, but I don't have any QS series speakers yet.

Like grunt, I'm finding that I like the sound better using the Flat curve on my Denon 590 than the Audyssey curve. I'd imagine that you would be able to select between the different curves on the 3808 with just a push of a button. I can go between Audyssey, Flat, Manual, and Off by pressing the MultEQ button on my remote.