I've listened to the M22s v2 with a sub and they are not equivalent to M80s v2. There are big differences in soundstage, presence and mid-range. I find the M22 v2 "thin" or "lean" compared to the M80 v2. I can't speak to other versions.

House of the Rising Sone
Out in the mid or far field
Dedicated mid-woofers are over-rated