I have a M2/VP150/EP500 setup for a 77” tv in my family room. The room is 18x18’ but only 1/2 is used for tv viewing (other 1/2 ping pong) … even in that large space that combo sounds great. Oh … its 5.1 … a pair of QS10s are on the back wall.
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I would definitely go with the M2 on-walls with a sub. A phantom center vs a real one is dependent on how many seats get a decent image. If it’s only you then go phantom. If your going for more then 2 seats then a real center my be required … I’m happy with my VP150v4. The QS10s are killer for 5.1 and 7.1 setups. They have exceeded my expectations in this room.

The other options are also fine … I’ve listened to M5ow’s and M3ow’s sitting where the M2’s are in the picture above and both sounded great … although I only listened with the ep500 …