Hi Bill
I am using the 60's in a 2 channel setup and I absolutely love them. They replaced a pair of Paradigm Monitor 7's which I had for 6 years. I liked my 7's but I found that they lacked in midrange clarity. I can tell you that the 60's reproduce vocals with unbelievable clarity and detail, bass is tight and accurate too.

Sorry, I've never had a bookshelf + sub setup so I can't comment, but I'm sure others will chime in.

Also, it wouldn't hurt to know your room size
Al