A crossover would not be a question if you don't have a sub. You would be running the 22's as large, so they would be getting the full range. If you get a sub, and your only option on your receiver is 100hz, that would probably be ok, since the sub would pick up everything below that...many people use m3's or m22's for music only without a sub. Depending on your music types, the 22's will go down below 60hz, so you would be fine.

M80s VP180 4xM22ow 4xM3ic EP600 2xEP350
AnthemAVM60 Outlaw7700 EmoA500 Epson5040UB FluanceRT85