Arthur:
Welcome to the forums! I have never heard the M22s but have read lots of reports on them and think you'll be thrilled. If you're not planning on cranking the whole system to ear-bleeding levels and the system is really for music, I would recommend the EP350 sub instead of the 500. It'll save you a few bucks, has an excellent reputation for being articulate, and though it won't go as low as the 500, it'll go plenty low enough for music!

::::::: No disrespect to Axiom, but my favorite woofer is my yellow lab :::::::