That's a big room for a 350. I'd be looking at dual 500's. But it depends on room. Maybe get away dual 350's. Only one way to find out....try it. If you are planning Atmos go direct firing...no qs8 or 10. You'll save some money there. Big rooms = big money to make sound equal to small room. Keep in mind the vp180 needs 4 ohm amps. More $$$. I'll have a 160 soon and I'll see if it's worth the jump from the 150