How our brain interprets sound is ultimately a chemical process which is impacted by more than anyone currently understands. Intestinal peptides for example play a big role and those are controlled by your lifestyle (eating, exercising, sleeping, etc). When we figure out exactly how our brain interprets sound, we won't need room correction; we'll be able to "take a pill".

House of the Rising Sone
Out in the mid or far field
Dedicated mid-woofers are over-rated