You may be guessing wrong, Alex. First, there's the separate calibration step which doesn't involve room EQ. Also, even assuming that there would be a conflict between the DSP processing on the LFR1100s and the Audyssey room EQ processing on them which would make it inadvisable to combine them, the Audyssey processing in most implementations can be set to bypass any EQ on the front speakers and apply it only to the other speakers.

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Enjoy the music, not the equipment.